Studies on the dissociation of botulinum neurotoxin type A complexes (ENG)
30.12.2013
BoNT A toxin complexes have evolved to quickly respond to specific environmental changes by efficient release of the neurotoxin. During pharmaceutical production and reconstitution of BoNT A products, the same principles effect the quantitative dissociation of 900 kDa complexes and release of free neurotoxin prior to injection into target tissues. Copyright © 2011 Elsevier Ltd. All rights reserved.
Автор: Eisele KH, Fink K, Vey M, Taylor HV.
Год публикации: 2010
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